Wednesday, November 28, 2007

BACKGROUND OF IMMUNE SYSTEM

Concept came from biological background
Very important computational perspective.
Nervous system
inspired the development of ANN
Immune system
Led to the emergence of AIS as a novel computational intelligence paradigm.
Artificial immune systems developed using ideas, theories, and components, extracted from the immune system.

WHAT IMMUNE SYSTEM DOES?
All living organisms are capable of presenting some type of defense against foreign attack.
Main task
Search for malfunctioning cells from their own body (e.g., cancer and tumour cells), and foreign disease causing elements (e.g., viruses and bacteria)
Made up by great variety of molecules, cells, and organs spread all over the body

NEGATIVE SELECTION

After T-cells are generated, they migrate into the thymus where they mature. During this maturation, all T-cells that recognize self-antigens are excluded from population of T-cells; a process termed negative selection.
Negative selection presents an alternative paradigm to perform pattern recognition by storing information about the complement set (non self) of the patterns to be recognized (self)

No comments: